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Publications
Additional information on any of these publications can be obtained from Brixham Environmental Laboratory
Some recent scientific publications by people at Brixham Environmental Laboratory are listed below.
Defining the chronic impacts of Atenolol on embryo-larval development and reproduction in the fathead minnow (Pimephales promelas).
Winter M.J. ; Lillicrap A.D. ; Caunter J.E. ; Schaffner C. ; Alder A. ; Ramil M. ; Ternes T. ; Giltrow E. ; Sumpter J.P. ; Hutchinson T.H.
Aquatic Toxicology 86 v3 (2008) 361 - 369
Kinetics and degradation products for direct photolysis of beta-blockers in water.
Q.T. Liu, H. Williams 2007
Environmental Science and Technology, 41, 803 - 810.
Comparative abiotic and biotic degradation of beta-blockers in river waters
Q-T Liu, P. McCormack, R.I. Cumming, M.J. Hetheridge, A.D. Sharpe
Positioning phototransformation for environmental risk assessment of pharmaceuticals, Marcus Evans 2nd Pharma Environmental Forum: Streamlining co-operation between indusrty and agency to enhance environmental risk assessment process
Q-T. Liu
Amsterdam 13 - 14 March 2008 Invited speech
Effects of Human Pharmaceuticals on Aquatic Life: Next Steps.
Cunninghan V.L. ; Buzby M. ; Hutchinson T.H. ; Mastrocco F. ; Parke N. ; Roden N.
Environmental Science and Technology 2006 v40 n11 p3456 -3462
Development of chronic tests for endocrine active chemicals. Part 1. An extended fish early-life stage test for oestrogenic active chemicals in the fathead minnow (Pimephales promelas).
Panter G.H. ; Hutchinson T.H. ; Bamforth J.E. ; Stanley R. ; Duffell S. ; Hargreaves A. ; Gimeno S. ; Tyler C.R.
Aquatic Toxicology 2006 v77 p279 -290
Comparative physiology, pharmacology and toxicology of beta-blockers: Mammals versus fish
Owen S.F. ; Giltrow E. ; Huggett D.B. ; Hutchinson T.H. ; Saye J.A. ; Winter M.J. ; Sumpter J.P
Aquatic Toxicology 82 (2007) 145 - 162
Pharmaceuticals in the Environment: What is the Pharmaceutical Industry Doing?
Taylor D.
DIA 5th Canadian Annual Meeting, Ottowa, October 2007
Small is useful in endocrine disrupter assessment - four key recommendations for aquatic invertebrate research.
Hutchinson T.H.
Ecotoxicology 2006 v16 n1 p231 -238
Assessing the environmental effects of human pharmaceuticals: An overview of current practice and opportunities for improved approaches.
Hutchinson T.H.
Tamiflu workshop, Oxford UK. 3 October 2007
Development and validation of a direct homologous quantitative sandwich ELISA for fathead minnow (Pimephales promelas) vitellogenin.
Eidem J.K. ; Kleivedal H. ; Kroll K. ; Denslow N. ; van Aerle R. ; Tyler C.R. ; Panter G.H. ; Hutchinson T.H. ; Goksoyr A.
Aquatic Toxicology 2006 v78 n2 p202 -206
Availability of in vitro vitellogenin assay for screening of estrogenic and anti- estrogenic activities of environmental chemicals.
Iguchi T. ; Irie F. ; Urushitani H. ; Tooi O. ; Kawashima Y. ; Roberts M. ; Norrgren L ; Hutchinson T.H.
Environmental Sciences 2006 v13 p161 -183
Population growth rate and carrying capacity for Springtails Folsomia candida exposed to Ivermectin.
Noel H. ; Hopkin S. ; Hutchinson T.H. ; Williams T.D. ; Sibly R.
Ecological Applications 2006 v16 n2 p656 -665
Modelling the Impact of Direct Phototransformation on Predicted Environmental Concentrations (PECs) of Propranolol hydrochloride in UK and US Rivers.
Paul F. Robinson, Qin-Tao Liu, Andrew M. Riddle, Richard Murray-Smith
Chemosphere 2007 v66 p757 -766
Blood and Spleen micronucleus assessment in the fathead minnow (Pimephales promelas), after injection with mitomycin C or cyclophosphamide.
Winter M.J. ; Ellis L.C.J. ; Hutchinson T.H.
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Volume 629, Issue 2 18 May 2007, Page 89 - 99
Human health and environmental risk assessment of carmazepine in surface waters of North America and Europe.
Cunningham V. ; Hartmann A. ; D'Aco V. ; Perino C. ; Hutchinson T.H. ; Bechter R.
Environmental Science and Technology (In Press) 2007
Molecular and population stress responses of Daphnia magna exposed to cadmium.
Connon R. ; Hooper H.L. ; Sibly R.M. ; Lim F.L. ; Moore D.J. ; Watanabe H. ; Soetaert A. ; Hutchinson T.H. ; Moggs J. ; Callaghan A.
Ecotoxicology (In Press) 2007
Uptake of Propranolol, a cardiovascular pharmaceutical, from water into fish plasma and its effects on growth and organ biometry.
Owen S.F. ; Huggett D.B. ; Hutchinson T.H. ; Hetheridge M.J. ; Kinter L.B. ; Ericson J.F. ; Sumpter J.P.
Toxicological Science (In Press) 2007
Chronic toxicity of ibuprofen to Daphnia magna: effects on life history traits and population dynamics.
Heckmann L.H. ; Callaghan A. ; Hooper H.L. ; Connon R. ; Hutchinson T.H. ; Maund S.J. ; Sibly R.M.
Volume 172 Issue 3 pp 137 - 145
Workshop on the use and modeling and monitoring in the environmental risk assessment of human medicines.
Murray-Smith R.J. ; Ramil M.
Drug Information Journal 2007 v41 p2 -195
Guest Editorial: DIA/HESI/SAPS Conference on environmental risk assessment of human medicines (Stockholm, May 22-23, 2006).
Drug Information Journal 2007 v41 p2 -129
Editor(s) : Montforts M; Spindler P.;Taylor D.; Williams R.
Summary of workshop on environmental assessment of human medicines: Development and use of aquatic toxicity data.
Montforts M.H.M.M. ; Brandt I. ; Hutchinson T.H.
Drug Information Journal 2007 v41 p2 -203
Evaluation of the reproductive effects of tamoxifen citrate in partial and full life-cycle studies using fathead minnows (Pimephales promelas).
Environmental Toxicology and Chemistry 2007 v26 n4 p695 -707
Defining the chronic impacts of Atenolol (Tenormin) on embryo-larval development and reproduction in the fathead minnow (Pimephales promelas).
Winter M.J. ; Lillicrap A.D. ; Caunter J.E. ; Hutchinson T.H. ; Alder A. ; Ramil M.; Ternes T. ; Giltrow E. ; Sumpter J.P.
Aquatic Toxicology (In Press) 2007
The effects of environmental contaminants in fish: an in vitro approach.
PhD Thesis 2007
Realising the potential benefits of small animal models for the aquatic hazard assessment of human pharmaceuticals: A conceptual approach.
(PIE Book) 2008
Editor(s) :Kuemmerer K.
Ecotoxicogenomics: the challenge of integrating genomics into aquatic and terrestrial ecotoxicology
Jason Snape, Steve J. Maund , Daniel B. Pickford, Thomas H. Hutchinson 2004
Aquatic Toxicology 67, 2 , p 143-154

