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Publications

Additional information on any of these publications can be obtained from Brixham Environmental Laboratory

Some recent scientific publications by people at Brixham Environmental Laboratory are listed below.

Defining the chronic impacts of Atenolol on embryo-larval development and reproduction in the fathead minnow (Pimephales promelas).

Winter M.J. ; Lillicrap A.D. ; Caunter J.E. ; Schaffner C. ; Alder A. ; Ramil M. ; Ternes T. ; Giltrow E. ; Sumpter J.P. ; Hutchinson T.H.

Aquatic Toxicology 86 v3 (2008) 361 - 369


Kinetics and degradation products for direct photolysis of beta-blockers in water.

Q.T. Liu, H. Williams 2007

Environmental Science and Technology, 41, 803 - 810.


Comparative abiotic and biotic degradation of beta-blockers in river waters

Q-T Liu, P. McCormack, R.I. Cumming, M.J. Hetheridge, A.D. Sharpe

SETAC Europe 2007


Positioning phototransformation for environmental risk assessment of pharmaceuticals, Marcus Evans 2nd Pharma Environmental Forum: Streamlining co-operation between indusrty and agency to enhance environmental risk assessment process

Q-T. Liu

Amsterdam 13 - 14 March 2008 Invited speech


Effects of Human Pharmaceuticals on Aquatic Life: Next Steps.

Cunninghan V.L. ; Buzby M. ; Hutchinson T.H. ; Mastrocco F. ; Parke N. ; Roden N.

Environmental Science and Technology 2006 v40 n11 p3456 -3462


Development of chronic tests for endocrine active chemicals. Part 1. An extended fish early-life stage test for oestrogenic active chemicals in the fathead minnow (Pimephales promelas).

Panter G.H. ; Hutchinson T.H. ; Bamforth J.E. ; Stanley R. ; Duffell S. ; Hargreaves A. ; Gimeno S. ; Tyler C.R.

Aquatic Toxicology 2006 v77 p279 -290


Comparative physiology, pharmacology and toxicology of beta-blockers: Mammals versus fish

Owen S.F. ; Giltrow E. ; Huggett D.B. ; Hutchinson T.H. ; Saye J.A. ; Winter M.J. ; Sumpter J.P

 

Aquatic Toxicology 82  (2007) 145 - 162


Pharmaceuticals in the Environment: What is the Pharmaceutical Industry Doing?

Taylor D.

DIA 5th Canadian Annual Meeting, Ottowa, October 2007


Small is useful in endocrine disrupter assessment - four key recommendations for aquatic invertebrate research.

Hutchinson T.H.

Ecotoxicology 2006 v16 n1 p231 -238


Assessing the environmental effects of human pharmaceuticals: An overview of current practice and opportunities for improved approaches.

Hutchinson T.H.

Tamiflu workshop, Oxford UK. 3 October 2007


Development and validation of a direct homologous quantitative sandwich ELISA for fathead minnow (Pimephales promelas) vitellogenin.

Eidem J.K. ; Kleivedal H. ; Kroll K. ; Denslow N. ; van Aerle R. ; Tyler C.R. ; Panter G.H. ; Hutchinson T.H. ; Goksoyr A.

Aquatic Toxicology 2006 v78 n2 p202 -206


Availability of in vitro vitellogenin assay for screening of estrogenic and anti- estrogenic activities of environmental chemicals.

Iguchi T. ; Irie F. ; Urushitani H. ; Tooi O. ; Kawashima Y. ; Roberts M. ; Norrgren L ; Hutchinson T.H.

Environmental Sciences 2006 v13 p161 -183


Population growth rate and carrying capacity for Springtails Folsomia candida exposed to Ivermectin.

Noel H. ; Hopkin S. ; Hutchinson T.H. ; Williams T.D. ; Sibly R.

Ecological Applications 2006 v16 n2 p656 -665


Modelling the Impact of Direct Phototransformation on Predicted Environmental Concentrations (PECs) of Propranolol hydrochloride in UK and US Rivers.

Paul F. Robinson, Qin-Tao Liu, Andrew M. Riddle, Richard Murray-Smith

Chemosphere 2007 v66 p757 -766


Blood and Spleen micronucleus assessment in the fathead minnow (Pimephales promelas), after injection with mitomycin C or cyclophosphamide.

Winter M.J. ; Ellis L.C.J. ; Hutchinson T.H.

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Volume 629, Issue 2 18 May 2007, Page 89 - 99


Human health and environmental risk assessment of carmazepine in surface waters of North America and Europe.

Cunningham V. ; Hartmann A. ; D'Aco V. ; Perino C. ; Hutchinson T.H. ; Bechter R.

Environmental Science and Technology (In Press) 2007


Molecular and population stress responses of Daphnia magna exposed to cadmium.

Connon R. ; Hooper H.L. ; Sibly R.M. ; Lim F.L. ; Moore D.J. ; Watanabe H. ; Soetaert A. ; Hutchinson T.H. ; Moggs J. ; Callaghan A.

Ecotoxicology (In Press) 2007


Uptake of Propranolol, a cardiovascular pharmaceutical, from water into fish plasma and its effects on growth and organ biometry.

Owen S.F. ; Huggett D.B. ; Hutchinson T.H. ; Hetheridge M.J. ; Kinter L.B. ; Ericson J.F. ; Sumpter J.P.

Toxicological Science (In Press) 2007


Chronic toxicity of ibuprofen to Daphnia magna: effects on life history traits and population dynamics.

Heckmann L.H. ; Callaghan A. ; Hooper H.L. ; Connon R. ; Hutchinson T.H. ; Maund S.J. ; Sibly R.M.

Toxicology Letters

Volume 172 Issue 3 pp 137 - 145


Workshop on the use and modeling and monitoring in the environmental risk assessment of human medicines.

Murray-Smith R.J. ; Ramil M.

Drug Information Journal 2007 v41 p2 -195


Guest Editorial: DIA/HESI/SAPS Conference on environmental risk assessment of human medicines (Stockholm, May 22-23, 2006).

Drug Information Journal 2007 v41 p2 -129

Editor(s) : Montforts M; Spindler P.;Taylor D.; Williams R.


Summary of workshop on environmental assessment of human medicines: Development and use of aquatic toxicity data.

Montforts M.H.M.M. ; Brandt I. ; Hutchinson T.H.

Drug Information Journal 2007 v41 p2 -203


Evaluation of the reproductive effects of tamoxifen citrate in partial and full life-cycle studies using fathead minnows (Pimephales promelas).

Williams T.D.; Caunter J.E. ; Lillicrap A.D. ; Hutchinson T.H.; Gillings E.; Duffell S.

Environmental Toxicology and Chemistry 2007 v26 n4 p695 -707


Defining the chronic impacts of Atenolol (Tenormin) on embryo-larval development and reproduction in the fathead minnow (Pimephales promelas).

Winter M.J. ; Lillicrap A.D. ; Caunter J.E. ; Hutchinson T.H. ; Alder A. ; Ramil M.; Ternes T. ; Giltrow E. ; Sumpter J.P.

Aquatic Toxicology (In Press) 2007


The effects of environmental contaminants in fish: an in vitro approach.

Bickley L.K.

PhD Thesis 2007


Realising the potential benefits of small animal models for the aquatic hazard assessment of human pharmaceuticals: A conceptual approach.

Hutchinson T.H.

(PIE Book) 2008

Editor(s) :Kuemmerer K.


Ecotoxicogenomics: the challenge of integrating genomics into aquatic and terrestrial ecotoxicology

Jason Snape, Steve J. Maund , Daniel B. Pickford, Thomas H. Hutchinson 2004

Aquatic Toxicology 67, 2 , p 143-154


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